INFLUENCING OF NEW REHABILITATION "REOMANNISOL" ON LIPID PEROXIDATION AND ANTIOXIDANT SYSTEM IN EXPERIMENTAL HEMOLITIC ANEMIA
DOI:
https://doi.org/10.61841/n95pjy91Keywords:
hemolytic anemia, experiment, rats, phenylhydrazine, LPO, Reomannisol, AOSAbstract
Goal of the research: to conduct a comparative assessment of the effectiveness of the new Reomannisol blood substitute on the state of lipid peroxidation and antioxidant system indicators in hemolytic anemia in the experiment. Materials and methods. On white laboratory rats (n = 120, average body weight 178.5 ± 5.8 g.), A model of hemolytic anemia was reproduced by a single intraperitoneal administration of a 2% solution of phenylhydrazine at a dose of 50 mg / kg of animal weight. In laboratory animals, the parameters of antioxidant protection and lipid components in the blood were studied. Results. In a comparative study of the new Reomannisol blood substitute, it was proved that it restores the state of lipid peroxidation and the activity of AOS enzymes in hemolytic anemia, more effective than other analogues and can be used in medical practice, in pathological conditions associated with hypoxic conditions.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
