Follicular Unit Extraction with or without Platelet Rich Plasma in the Treatment of and Rogenetic Alopecia
DOI:
https://doi.org/10.61841/xs0xfz90Keywords:
Follicular Unit Extraction (FUE), Platelet Rich Plasma (PRP), Androgenetic Alopecia (AGA).Abstract
Androgenetic alopecia (AGA) is a genetically determined phenomenon that is defined by gradual loss and reduction of normal thick hair follicles. This study aimed to determine if Platelet Rich Plasma (PRP) assists in Follicular Unit Extraction (FUE) or not This is a prospective comparative study that was performed in the period from January 2019 to January 2020 in Plastic & Reconstructive Surgery Department of Zagazig University Hospitals. This study included 16 patients with androgenic alopecia checked at Plastic Surgery Outpatient Clinic, Zagazig University Hospitals. Patients included in the study was divided into two groups according to receiving RPR or not, Group (1); 8 Patients treated with FUE with PRP. Group (2); 8 Patients treated with FUE without PRP.
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References
1. Cervelli V, Garcovich S, Bielli A, Cervelli G, Curcio BC, Scioli MG, et al. The effect of autologous activated
platelet rich plasma (AA-PRP) injection on pattern hair loss: Clinical and histomorphometric evaluation.
Biomed Res Int 2014. 2014; 760-709.
2. Navarro RM, Pino A, Martinez-Andres A, Molina C, Martinez AM, Martinez N, et al. The effect of plasma
rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot
study. J Cosmet Dermatol. 2018; 17(5): 862–73.
3. Anitua E, Orive G. Endogenous regenerative technology using plasma-and platelet-derived growth factors. J
Controlled Release. 2012; (157) 317-320.
4. Jain R, De-Eknamkul W. Potential targets in the discovery of new hair growth promoters for androgenic
alopecia. Expert Opin Ther Targets. 2014; 18: 787–806.
5. Rastegar H, Ahmadi Ashtiani H, Aghaei M, Ehsani A, Barikbin B. Combination of herbal extracts and
platelet‐rich plasma induced dermal papilla cell proliferation: Involvement of ERK and Akt pathways. J
Cosmet Dermatol. 2013; 12: 116‐122.
6. Garg S. Outcome of Intra-operative Injected Platelet-rich Plasma Therapy During Follicular Unit Extraction
Hair Transplant: A Prospective Randomised Study in Forty Patients. J Cutan Aesthet Surg. 2016; 9(3): 157–
164.
7. Uebel CO, Da Silva JB, Cantarelli D, Martins P. The role of platelet plasma growth factors in male pattern
baldness surgery. Plast Reconstr Surg. 2006; (118) 1458-1466.
8. Rahmani W, Abbasi S, Hagner A, Raharjo E, Kumar R, Hotta A, et al. Hair follicle dermal stem cells
regenerate the dermal sheath, repopulate the dermal papilla, and modulate hair type. Dev Cell. 2014;
31:543‐58.
9. Tohidnezhad M, Wruck C‐J, Slowik A, Kweider N, Beckmann R, Bayer A, et al. Role of platelet‐released
growth factors in detoxification of reactive oxygen species in osteoblasts. Bone. 2014; 65: 9‐17.
10. Li, ZJ, Choi HI, Choi DK, Sohn KC, Im M, Seo YJ, et al. Autologous platelet‐rich plasma: a potential
therapeutic tool for promoting hair growth. Dermatol Surg. 2012; 38:1040‐6.
11. Arshdeep, Kumaran MS. Platelet-rich plasma in dermatology: Boon or a bane? Indian J Dermatol Venereol
Leprol. 2014; 80:5–14.
12. Kang JS, Zheng Z, Choi MJ, Lee SH, Kim DY, Cho SB. The effect of CD34+cell-containing autologous
platelet-rich plasma injection on pattern hair loss: A preliminary study. J Eur Acad Dermatol Venereol. 2014;
28: 72–9
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