NANOCHITOSAN AND DENTAL BIOFILMS – A REVIEW

Authors

  • MAYMA NATHASHA M Postgraduate student, Department of Orthodontics, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India. Author
  • SANGEETHA DURAISAMY Reader, Department of Orthodontics, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India. Author
  • RAVI KANNAN Reader, Department of Orthodontics, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India. Author

DOI:

https://doi.org/10.61841/pbn79623

Keywords:

Chitosan, Nanochitosan, Antimicrobial agent, Dental biofilms

Abstract

 Dental biofilms harbor harmful microorganisms that causes dental caries and periodontal diseases.
Chitosan is a naturally occurring polysaccharide with antimicrobial properties against a wide
spectrum of bacteria and fungus. Chitosan nanoparticles possess unique physicochemical
characteristics, when utilized properly can be used to prevent the formation or reduction of plaque
bio mass by acting against the microbes present in the plaque and disruption of mature biofilm. 

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References

1. Elieh-Ali-Komi D, Hamblin MR. Chitin and chitosan: production and application of versatile

biomedical nanomaterials. International journal of advanced research. 2016 Mar;4(3):411

2. El-Diasty EMN, Eleiwa Z, Hoda AM. Aideia Using of Chitosan as Antifungal Agent in

Kariesh Cheese. New York Science Journal. 2012

3. Park BK, Kim MM. Applications of chitin and its derivatives in biological medicine.

International journal of molecular sciences. 2010; 11(12):5152–64.

4. El-hefian EA, Nasef MM, Yahaya AH. Chitosan physical forms: a short review. Australian

Journal of Basic and Applied Sciences. 2011 May;5(5):670-7

5. Raafat D, Sahl H-G. Chitosan and its antimicrobial potential e a critical literature survey.

Microbiol Biotechnol 2009;2(2):186e201

6. Ikono R, Vibriani A, Wibowo I, Saputro KE, Muliawan W, Bachtiar BM, Mardliyati E,

Bachtiar EW, Rochman NT, Kagami H, Xianqi L. Nanochitosan antimicrobial activity against

Streptococcus mutans and Candida albicans dual-species biofilms. BMC research notes. 2019

Dec;12(1):1-7.

7. CriniG. Historical review on chitin and chitosan biopolymers. Environmental Chemistry

Letters. 2019 Dec 1:1-21.

8. TanikondaR, Ravi RK, KanthetiS, DivellaS. Chitosan: Applications in Dentistry. Trends in

Biomaterials &Artificial Organs. 2014 Apr1;28(2).

9. Cheung RC, Ng TB, Wong JH, Chan WY. Chitosan: an update on potential biomedical and

pharmaceutical applications. Marine drugs. 2015Aug;13(8):5156 -86

10. Morin-Crini N, Lichtfouse E, Torri G, Crini G. Applications of chitosan in food,

pharmaceuticals, medicine, cosmetics, agriculture, textiles, pulp and paper, biotechnology,

and environmental chemistry. Environmental Chemistry Letters. 2019 Dec;17(4):1667-92.

11. Pasquantonio G, Greco C, Prenna M, Ripa C, Vitali LA, Petrelli D, Di Luca MC, Ripa S.

Antibacterial activity and anti-biofilm effect of chitosan against strains of Streptococcus

mutans isolated in dental plaque. International Journal of Immunopathology and

Pharmacology. 2008 Oct;21(4):993-7.

12. Costa EM, Silva S, Tavaria FK, Pintado MM. Study of the effects of chitosan upon

Streptococcus mutans adherence and biofilm formation. Anaerobe. 2013 Apr 1;20:27-31.

13. Mohire NC, Yadav AV. Chitosan-based polyherbal toothpaste: as novel oral hygiene product.

Indian Journal of Dental Research. 2010 Jul 1;21(3):380.

14. Uysal T, Akkurt MD, Amasyali M, Ozcan S, Yagci A, Basak F, Sagdic D. Does a chitosancontaining dentifrice prevent demineralization around orthodontic brackets?. The Angle

Orthodontist. 2011 Mar 1;81(2):319-25.

15. PerchyonokVT, FelittiR, Zhang S. Chitosan bio -active designer materials and orthodontics:

development and evaluation of novel materialsas enamel protective agents.

BiointerfaceResearchinAppliedChemistry. 2016 May 1;6(3):1303-7.

16. Elsaka SE. Antibacterial activity and adhesive properties of a chitosan-containing dental

adhesive. Quintessence International. 2012 Jul 1;43(7).

17. Diolosà M, Donati I, Turco G, Cadenaro M, Di Lenarda R, Breschi L, Paoletti S. Use of

methacrylate-modified chitosan to increase the durability of dentine bonding systems.

Biomacromolecules. 2014 Dec 8;15(12):4606-13.

18. Bumgardner JD, Wiser R, Gerard PD, Bergin P, Chestnutt B, Marini M, Ramsey V, Elder SH,

Gilbert JA. Chitosan: potential use as a bioactive coating for orthopaedic and

craniofacial/dental implants. Journal of Biomaterials Science, Polymer Edition. 2003 Jan

1;14(5):423-38.

19. Bougueraa FZ, Ettaqi S. Chitosan based coating on the pur titanium substrate/dental

application. InECCM16-16 The Uropean Conference On Composite Materials, Seville, Spain

2014 (pp. 22-26).

20. MareciD, CimpoesuN, PopaMI. Electrochemical and SEM characterization of NiTi alloy

coated with chitosan by PLD technique. Materials and Corrosion. 2012 Nov;63(11):985-91.

21. Kawaguchi K, IijimaM, Miyakawa H,OhtaM,MugurumaT, Endo K, Nakazawa F, Mizoguchi

I. Effects of chitosan fiber addition on the propertiesof polyurethane with thermo‐responsive

shape memory. Journal of Biomedical MaterialsResearchPartB: Applied Biomaterials.

2017Jul;105(5):1151 -6.

22. Villegas-Peralta Y, López-Cervantes J, Santana TJ, Sánchez-Duarte RG, Sánchez-Machado

DI, del Rosario Martínez-Macías M, Correa-Murrieta MA. Impact of the molecular weight on

the size of chitosan nanoparticles: Characterization and its solid-state application. Polymer

Bulletin. 2021 Feb;78(2):813-32.

23. Roy SG, Shirsat NS, Mishra AC, Waghulde SO, Kale MK. A review on chitosan

nanoparticles applications in drug delivery. J Pharm. Phytochem. 2018;7:1-4.

24. Dobhal A, Bangde P, Dey A, Dandekar P, Jain R. Chitosan-based nanoparticulate systems:

implication towards therapeutics application. InParticulate Technology for Delivery of

Therapeutics 2017 (pp. 167-225). Springer, Singapore.

25. Jhaveri J, Raichura Z, Khan T, Momin M, Omri A. Chitosan Nanoparticles-Insight into

Properties, Functionalization and Applications in Drug Delivery and Theranostics. Molecules.

2021 Jan;26(2):272.

26. Qi L, Xu Z, Jiang X, Hu C, Zou X. Preparation and antibacterial activity of chitosan

nanoparticles. Carbohydrate research. 2004 Nov 15;339(16):2693-700.

27. Kassaee M, Hosseini S, Elahi SH, Bolhari B. A new nano-chitosan irrigant with superior

smear layer removal and penetration. Nanochemistry Research. 2016 Jul 1;1(2):150-6.

28. Mirhashemi A, Bahador A, Kassaee M, Daryakenari G, Ahmad-Akhoundi M, Sodagar A.

Antimicrobial effect of nano-zinc oxide and nano-chitosan particles in dental composite used

in orthodontics. Journal of Medical Bacteriology. 2013;2(3-4):1-0.

29. Sodagar A, Bahador A, Jalali YF, Gorjizadeh F, Baghaeian P. Effect of chitosan nanoparticles

incorporation on antibacterial properties and shear bond strength of dental composite used in

orthodontics. Iran J Ortho. https://doi. org/10.17795/ijo-7281. 2016.

30. Sodagar A, Akhavan A, Pourhajibagher M, Bahador A. Antibacterial Effects of Orthodontic

Primer Harboring Chitosan Nanoparticles against the Multispecies Biofilm of Cariogenic

Bacteria in a Rat Model. Folia Medica. 2020 Dec 31;62:817.

31. Kumar RS, Ravikumar N, Kavitha S, Mahalaxmi S, Jayasree R, Kumar TS, Haneesh M.

Nanochitosan modified glass ionomer cement with enhanced mechanical properties and

fluoride release. International journal of biological macromolecules. 2017 Nov 1;104:1860-5.

32. Kritika S, Jothimani B, Vidhya S, Sanjeev K, Mahalaxmi S, Venkatachalapathy B,

Sureshkumar S. Incorporation of hydrophobic nanochitosan improves wear resistance of

dental sealants. International Journal of Polymeric Materials and Polymeric Biomaterials.

2020 Jan 13:1-9.

33. Sadeghi Ardestani Z, Falahati M, Sayah Alborzi S, Ashrafi Khozani M, Bahador A. The

effect of nanochitosans particles on Candida biofilm formation. Current Medical Mycology.

2016;2(2):28-33.

34. Triawan A, Pudyani PS, HNE SM. The effect of nanochitosan hydrogel membrane on

absorbtion of nickel, inhibition of Streptococcus mutans and Candida albicans. Dental Journal

(Majalah Kedokteran Gigi). 2015 Mar 31;48(1):26-30.

35. Allaker RP. The use of nanoparticles to control oral biofilm formation. Journal of dental

research. 2010 Nov;89(11):1175-86.

36. Aranaz I, Mengíbar M, Harris R, Paños I, Miralles B, Acosta N, Galed G, Heras Á.

Functional characterization of chitin and chitosan. Current chemical biology. 2009 May

1;3(2):203-30.

37. De Paz LC, Resin A, Howard KA, Sutherland DS, Wejse PL. Antimicrobial effect of chitosan

nanoparticles on Streptococcus mutans biofilms. Applied and Environmental Microbiology.

2011 Jun 1;77(11):3892-5.

38. Aliasghari A, Khorasgani MR, Vaezifar S, Rahimi F, Younesi H, Khoroushi M. Evaluation of

antibacterial efficiency of chitosan and chitosan nanoparticles on cariogenic streptococci: an

in vitro study. Iranian journal of microbiology. 2016 Apr;8(2):93.

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Published

30.09.2024

How to Cite

NATHASHA M, M., DURAISAMY, S., & KANNAN, R. (2024). NANOCHITOSAN AND DENTAL BIOFILMS – A REVIEW. International Journal of Psychosocial Rehabilitation, 25(2), 1224-1232. https://doi.org/10.61841/pbn79623