PATTERN OF MINERALISATION - A REVIEW
DOI:
https://doi.org/10.61841/sjh5w933Keywords:
Enamel, Dentin, MineralizationAbstract
The tooth develops through different chronological stages. Collagen is the protein in connective tissue as well as in hard tissue, bone, dentin, cementum, and even the mineralizing ligament of the epiphyseal growth plate. Hard tissue is mineralized and has a firm intercellular framework. Tooth development and mineralization are processes that derive from different tissue interactions, such as ectodermal and mesenchymal. These interactions are responsible for the formation of unique structures with a specific chemical composition. Despite differences, mineralized tissues are similar, deriving from highly concentrated extracellular processes involving matrix proteins, proteases, and mineral ion fluxes that regulate mineral crystal nucleation, growth, and organization. There are two theories-—they are collagen template-mediated mineralization and matrix vesicle-mediated mineralization. Mineralized tissues are well-organized hierarchical structures that adapt to different stimuli to achieve a desired function. This study aims at explaining the complex chemical and biological mechanism that leads to the development of dental germs and teeth. It is impossible to pinpoint the exact moment when the process drifts or the aetiological causes of important diseases, such as the MIH, without a solid understanding of this long and fascinating process.
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References
1. Wiesmann HP, Meyer U, Plate U, Höhling HJ. Aspects of Collagen Mineralization in Hard Tissue
Formation [Internet]. International Review of Cytology. 2004. p. 121–56. Available from:
http://dx.doi.org/10.1016/s0074-7696(04)42003-8
2. Lowenstam HA, Weiner S. Transformation of Amorphous Calcium Phosphate to Crystalline Dahillite
in the Radular Teeth of Chitons [Internet]. Vol. 227, Science. 1985. p. 51–3. Available from:
http://dx.doi.org/10.1126/science.227.4682.51
3. Kuhn LT. Bone Mineralization [Internet]. Encyclopedia of Materials: Science and Technology. 2001.
p. 787–94. Available from: http://dx.doi.org/10.1016/b0-08-043152-6/00151-0
4. Smith CE. Cellular and Chemical Events During Enamel Maturation [Internet]. Vol. 9, Critical
Reviews in Oral Biology & Medicine. 1998. p. 128–61. Available from:
http://dx.doi.org/10.1177/10454411980090020101
5. Shree KH, Hema Shree K, Ramani P, Herald Sherlin, Sukumaran G, Jeyaraj G, et al. Saliva as a
Diagnostic Tool in Oral Squamous Cell Carcinoma – a Systematic Review with Meta Analysis [Internet]. Vol.
25, Pathology & Oncology Research. 2019. p. 447–53. Available from: http://dx.doi.org/10.1007/s12253-019-
00588-2
6. Abitha T, Santhanam A. Correlation between bizygomatic and maxillary central incisor width for
gender identification [Internet]. Vol. 22, Brazilian Dental Science. 2019. p. 458–66. Available from:
http://dx.doi.org/10.14295/bds.2019.v22i4.1775
7. Krishnan RP, Ramani P, Sherlin HJ, Sukumaran G, Ramasubramanian A, Jayaraj G, et al. Surgical
Specimen Handover from Operation Theater to Laboratory: A Survey. Ann Maxillofac Surg [Internet]. 2018
Jul;8(2):234–8. Available from: http://dx.doi.org/10.4103/ams.ams_51_18
8. Palati S, Ramani P, Herald. J. Sherlin, Gheena S, Don KR, Jayaraj G, et al. Age Estimation of an Individual Using Olze’s Method in Indian Population-A Cross-Sectional Study [Internet]. Vol. 13, Indian Journal of Forensic Medicine & Toxicology. 2019. p. 121. Available from: http://dx.doi.org/10.5958/0973-9130.2019.00179.8
9. Sarbeen JI, Insira Sarbeen J, Gheena S. Microbial variation in climatic change and its effect on human health [Internet]. Vol. 9, Research Journal of Pharmacy and Technology. 2016. p. 1777. Available from:http://dx.doi.org/10.5958/0974-360x.2016.00359.0
10. Harrita S, Santhanam A. Determination of Physical Height Using Clinical Crown Height of Deciduous Teeth [Internet]. Vol. 13, Indian Journal of Forensic Medicine & Toxicology. 2019. p. 23. Available from:
http://dx.doi.org/10.5958/0973-9130.2019.00255.x
11. Sukumaran G, Padavala S. Molar incisor hypomineralization and its prevalence [Internet]. Vol. 9,
Contemporary Clinical Dentistry. 2018. p. 246. Available from: http://dx.doi.org/10.4103/ccd.ccd_161_18
12. Palati S, Ramani P, Shrelin H, Sukumaran G, Ramasubramanian A, Don KR, et al. Knowledge,
Attitude and practice survey on the perspective of oral lesions and dental health in geriatric patients residing in
old age homes [Internet]. Vol. 31, Indian Journal of Dental Research. 2020. p. 22. Available from:
http://dx.doi.org/10.4103/ijdr.ijdr_195_18
13. Prasanna GE, Gheena S. A study of empathy across students from 4 health disciplines among 1st years
and Final years [Internet]. Vol. 9, Research Journal of Pharmacy and Technology. 2016. p. 1472. Available
from: http://dx.doi.org/10.5958/0974-360x.2016.00286.9
14. Uma PK, Ramani P, Herald. J. Sherlin, Gheena S, Jayaraj G, Don KR, et al. Knowledge about Legal
Aspects of Medical Negligence in India among Dentists– A Questionnaire Survey. Medico Legal Update
[Internet]. 2020 Apr 9 [cited 2020 Jun 12];20(1):111–5. Available from:
http://ijop.net/index.php/mlu/article/view/337
15. Hannah R, Ramani P, Herald. J. Sherlin, Ranjith G, Ramasubramanian A, Jayaraj G, et al. Awareness
about the use, Ethics and Scope of Dental Photography among Undergraduate Dental Students Dentist Behind
the lens [Internet]. Vol. 11, Research Journal of Pharmacy and Technology. 2018. p. 1012. Available from:
http://dx.doi.org/10.5958/0974-360x.2018.00189.0
16. Gunasekaran G, Abilasha R. TOOTH SENSITIVITY AMONG RESIDENTIAL UNIVERSITY
STUDENTS IN CHENNAI [Internet]. Asian Journal of Pharmaceutical and Clinical Research. 2016. p. 63.
Available from: http://dx.doi.org/10.22159/ajpcr.2016.v9s2.13228
17. Ahad M, Gheena S. Awareness, attitude and knowledge about evidence based dentistry among the
dental practitioner in Chennai city [Internet]. Vol. 9, Research Journal of Pharmacy and Technology. 2016. p.
1863. Available from: http://dx.doi.org/10.5958/0974-360x.2016.00380.2
18. Manohar J, Abilasha R. A Study on the Knowledge of Causes and Prevalance of Pigmentation of
Gingiva among Dental Students [Internet]. Vol. 10, Indian Journal of Public Health Research & Development.
2019. p. 95. Available from: http://dx.doi.org/10.5958/0976-5506.2019.01859.x
19. Sheriff KAH, Ahmed Hilal Sheriff K, Santhanam A. Knowledge and Awareness towards Oral Biopsy
among Students of Saveetha Dental College [Internet]. Vol. 11, Research Journal of Pharmacy and Technology.
2018. p. 543. Available from: http://dx.doi.org/10.5958/0974-360x.2018.00101.4
20. Boyde A. Enamel [Internet]. Teeth. 1989. p. 309–473. Available from: http://dx.doi.org/10.1007/978-3-
642-83496-7_6
21. Mouthwash Use and the Prevention of Plaque, Gingivitis and Caries [Internet]. Vol. 20, Oral Diseases.
2014. p. 1–68. Available from: http://dx.doi.org/10.1111/odi.12187
22. Jeremias F, Koruyucu M, Küchler EC, Bayram M, Tuna EB, Deeley K, et al. Genes expressed in dental
enamel development are associated with molar-incisor hypomineralization. Arch Oral Biol [Internet]. 2013
Oct;58(10):1434–42. Available from: http://dx.doi.org/10.1016/j.archoralbio.2013.05.005
23. Margolis HC, Kwak S-Y, Yamazaki H. Role of mineralization inhibitors in the regulation of hard
tissue biomineralization: relevance to initial enamel formation and maturation. Front Physiol [Internet]. 2014
Sep 10;5:339. Available from: http://dx.doi.org/10.3389/fphys.2014.00339
24. Linde A. Dentin matrix proteins: composition and possible functions in calcification. Anat Rec
[Internet]. 1989 Jun;224(2):154–66. Available from: http://dx.doi.org/10.1002/ar.1092240206
25. Linde A. Dentin mineralization and the role of odontoblasts in calcium transport. Connect Tissue Res [Internet]. 1995;33(1-3):163–70. Available from: http://dx.doi.org/10.3109/03008209509016997
26. Linde A, Goldberg M. Dentinogenesis [Internet]. Vol. 4, Critical Reviews in Oral Biology & Medicine.
1993. p. 679–728. Available from: http://dx.doi.org/10.1177/10454411930040050301
27. Fincham AG, Moradian-Oldak J, Simmer JP. The Structural Biology of the Developing Dental Enamel
Matrix [Internet]. Vol. 126, Journal of Structural Biology. 1999. p. 270–99. Available from:
http://dx.doi.org/10.1006/jsbi.1999.4130
28. Rönnholm E. The amelogenesis of human teeth as revealed by electron microscopy [Internet]. Vol. 6,
Journal of Ultrastructure Research. 1962. p. 249–303. Available from: http://dx.doi.org/10.1016/s0022-
5320(62)80036-7
29. Warshawsky H, Smith CE. Morphological classification of rat incisor ameloblasts [Internet]. Vol. 179,
The Anatomical Record. 1974. p. 423–45. Available from: http://dx.doi.org/10.1002/ar.1091790403
30. Crabb HSM, Darling AI. The gradient of mineralization in developing enamel [Internet]. Vol. 2,
Archives of Oral Biology. 1960. p. 308–IN19. Available from: http://dx.doi.org/10.1016/0003-9969(60)90073-x
31. Crawford PJM, Aldred M, Bloch-Zupan A. Amelogenesis imperfecta. Orphanet J Rare Dis [Internet].
2007 Apr 4;2:17. Available from: http://dx.doi.org/10.1186/1750-1172-2-17
32. Krishan K, Garg A, Kanchan T, Machado M, Rao A. Enamel hypoplasia and its role in identification of
individuals: A review of literature [Internet]. Vol. 6, Indian Journal of Dentistry. 2015. p. 99. Available from:
http://dx.doi.org/10.4103/0975-962x.155887
33. Rushton MA. HEREDITARY ENAMEL DEFECTS. Proc R Soc Med [Internet]. 1964 Jan;57:53–8.
Available from: https://www.ncbi.nlm.nih.gov/pubmed/14114178
34. Simmer JP, Hu Y, Lertlam R, Yamakoshi Y, -C. Hu JC. Hypomaturation Enamel Defects
inKlk4Knockout/LacZKnockin Mice [Internet]. Vol. 284, Journal of Biological Chemistry. 2009. p. 19110–21.
Available from: http://dx.doi.org/10.1074/jbc.m109.013623
35. Matalová E, Lungová V, Sharpe P. Development of Tooth and Associated Structures [Internet]. Stem
Cell Biology and Tissue Engineering in Dental Sciences. 2015. p. 335–46. Available from:
http://dx.doi.org/10.1016/b978-0-12-397157-9.00030-8
36. Molar Incisor Hypomineralization. Institute of Odontology [Internet]. Paperpile. [cited 2020 Jun 21].
Available from: https://paperpile.com/app/p/60f2fe1d-5e3e-0444-95f1-d3b6bdb790cb
37. Fagrell TG, Salmon P, Melin L, Norén JG. Onset of molar incisor hypomineralization (MIH). Swed
Dent J [Internet]. 2013;37(2):61–70. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23957140
38. Xie Z, Kilpatrick NM, Swain MV, Munroe PR, Hoffman M. Transmission electron microscope
characterisation of molar-incisor-hypomineralisation [Internet]. Vol. 19, Journal of Materials Science: Materials
in Medicine. 2008. p. 3187–92. Available from: http://dx.doi.org/10.1007/s10856-008-3441-2
39. Jedeon K, De la Dure-Molla M, Brookes SJ, Loiodice S, Marciano C, Kirkham J, et al. Enamel defects
reflect perinatal exposure to bisphenol A. Am J Pathol [Internet]. 2013 Jul;183(1):108–18. Available from:
http://dx.doi.org/10.1016/j.ajpath.2013.04.004
40. Crombie FA, Manton DJ, Palamara JEA, Zalizniak I, Cochrane NJ, Reynolds EC. Characterisation of
developmentally hypomineralised human enamel. J Dent [Internet]. 2013 Jul;41(7):611–8. Available from:
http://dx.doi.org/10.1016/j.jdent.2013.05.002
41. Elfrink MEC, ten Cate JM, Jaddoe VWV, Hofman A, Moll HA, Veerkamp JSJ. Deciduous molar
hypomineralization and molar incisor hypomineralization. J Dent Res [Internet]. 2012 Jun;91(6):551–5.
Available from: http://dx.doi.org/10.1177/0022034512440450
42. Kuscu OO, Sandalli N, Dikmen S, Ersoy O, Tatar I, Turkmen I, et al. Association of amoxicillin use
and molar incisor hypomineralization in piglets: visual and mineral density evaluation. Arch Oral Biol
[Internet]. 2013 Oct;58(10):1422–33. Available from: http://dx.doi.org/10.1016/j.archoralbio.2013.04.012
43. Sapir S, Shapira J. Dentinogenesis imperfecta: an early treatment strategy. Pediatr Dent [Internet]. 2001
May;23(3):232–7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/11447953
44. Carroll MKO, Duncan WK. Dentin dysplasia type I [Internet]. Vol. 78, Oral Surgery, Oral Medicine,
Oral Pathology. 1994. p. 375–81. Available from: http://dx.doi.org/10.1016/0030-4220(94)90071-x
45. Fulari SG, Tambake DP. Rootless teeth: Dentin dysplasia type I. Contemp Clin Dent [Internet]. 2013
Oct;4(4):520–2. Available from: http://dx.doi.org/10.4103/0976-237X.123063
46. Giansanti JS, David Allen J. Dentin dysplasia, Type II, or dentin dysplasia, coronal type [Internet].
Vol. 38, Oral Surgery, Oral Medicine, Oral Pathology. 1974. p. 911–7. Available from:
http://dx.doi.org/10.1016/0030-4220(74)90344-2
47. Farhat Yaasmeen Sadique Basha, Rajeshkumar S, Lakshmi T, Anti-inflammatory activity of Myristica
fragrans extract . Int. J. Res. Pharm. Sci., 2019 ;10(4), 3118-3120 DOI:
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