Evidence for exercise therapy in the treatment of depression and anxiety
DOI:
https://doi.org/10.61841/9rhvxt95Abstract
There has been over 25 years of systematic investigation examining the relationship between physical activity, especially aerobic exercise and weight training, and depression and anxiety. In this chapter, we first present the findings of the two most recent meta-analyses in the area of physical activity and depression and anxiety. Potential mechanisms by which exer- cise may reduce depression and anxiety are described. Depression and anxiety are associated with a high incidence of co- morbid somatic illnesses, especially cardiovascular diseases and type 2 diabetes. Positive effects of regular exercise on these diseases in individuals with depression and anxiety disorders are discussed. Finally, we offer evidence based recom- mendations for good clinical practice.
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Abrantes, A., Strong, D., Cohn, A., Cameron, A., Greenberg, B., Mancebo, M., et al. (2009). Acute changes in ob- sessions and compulsions following moderate-intensity aerobic exercise among patients with obsessive-com- pulsive disorder. Journal of Anxiety Disorders, 23, 923–927.
American College of Sports Medicine. (2009). A.C.S.M.’s guidelines for exercise testing and prescription (8th ed.).
Baltimore: Williams & Wilkins.
American Psychiatric Association. (2004). Diagnostic and statistical manual of mental disorders (4th ed.). Wash- ington, DC: American Psychiatric Association.
Barbour, K., Edenfield, T., & Blumenthal, J. (2007). Exercise as a treatment for depression and other psychiatric disorders: a review. Journal of Cardiopulmonary Rehabilitation and Prevention, 27, 359–367.
Biddle, S., & Mutrie, N. (2001). Psychology of physical activity. Determinants, well-being and interventions . Lon- don: Routledge.
Blumenthal, J., Babyak, M., Moore, K., Craighead, W., Herman, S., & Khatri, P., et al. (1999). Effects of exercise training on older patients with major depression. Archives of Internal Medicine, 159, 2349–2356.
Borg, G. (1998). External, physiological and psychological factors and perceived exertion. In G. Borg (Ed), Borg’s perceived exertion and pain scales (pp. 68–74). Champaign, IL: Human Kinetics.
Broocks, A., Bandelow, B., Pekrun, G., George, A., Meyer, T., & Bartmann, U. (1998). Comparison of aerobic ex- ercise, clomipramine, and placebo in the treatment of panic disorder. American Journal Psychiatry, 155, 603–609.
Brosse, A., Sheets, E., Lett, H., & Blumenthal, J. (2000). Exercise and the treatment of clinical depression in adults: Recent findings and future directions. Sports Medicine, 32, 741–760.
Brown, R., Abrantes, A., Strong, D., Mancebo, M., Menard, J., Rasmussen, S., et al. (2007). A pilot study of mod- erate-intensity aerobic exercise for obsessive compulsive disorder. Journal Nervous and Mental Disease, 195, 514–520.
Cotman, C., Berchtold, N., Christie, L. (2007). Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends in Neurosciences, 30, 464–472.
Dishman, R., Berthoud, H., Booth, F., Cotman, C., Edgerton, V., Fleshner, M., et al. (2006). Neurobiology of exer- cise. Obesity, 14, 345–356.
Edenfield, T. (2007). Exercise and mood: Exploring the role of exercise in regulating stress reactivity in bipolar dis- order. Unpublished doctoral dissertation. Orono: University of Maine.
Erickson, K., & Kramer, A. (2009). Aerobic exercise effects on cognitive and neural plasticity in older adults. Brit- ish Journal of Sports Medicine, 43, 22–24.
Fox, K. (2000). Self-esteem, self-perceptions and exercise. International Journal of Sport Psychology, 31, 228– 240.
Guyatt, G., Gutterman, D., Baumann, M., Addrizzo-Harris, D., Hylek, E., Phillips, B., et al. (2006). Grading strength of recommendations and quality of evidence in clinical guidelines: report from an American college of chest physicians task force. Chest, 129, 174–181.
Huang, K., Su, T., Chen, T., Chou, Y., & Bai, Y. (2009). Comorbidity of cardiovascular diseases with mood and anxiety disorder: A population based 4-year study. Psychiatry and Clinical Neurosciences, 63, 401–409.
Knapen, J., Sommerijns, E., Vancampfort, D., Sienaert, P., Pieters, G., Haake, P., et al. (2009). State anxiety and subjective well-being responses to acute bouts of aerobic exercise in patients with depressive and anxiety disorders. British Journal of Sports Medicine, 43, 756–759.
Knapen, J., Van de Vliet, P., Van Coppenolle, H., David, A., Peuskens, J., Pieters, G., et al. (2005). Comparison of changes in physical self-concept, global self-esteem, depression and anxiety following two different psycho- motor therapy programs in non-psychotic psychiatric inpatients. Psychotherapy and Psychosomatics, 74, 353–361.
Knapen, J., Van de Vliet, P., Van Coppenolle, H., Peuskens, J., & Pieters, G. (2003). Evaluation of cardio-respirat- ory fitness and perceived exertion for patients with depressive and anxiety disorders: A study on reliability. Disability and Rehabilitation, 25, 1312–1315.
Knol, M., Twisk, J., Beekman, A., Heine, R., Snoek, F., & Pouwer, F. (2006). Depression as a risk factor for the on- set of type 2 diabetes mellitus. A meta-analysis. Diabetologia, 49, 837–845.
Lett, H., Blumenthal, J., Babyak, M., Sherwood, A., Strauman, T., & Robins, C. (2004). Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment. Psychosomatic Medicine, 66, 305–315.
Liu-Ambrose, T., & Donaldson, M. (2009). Exercise and cognition in older adults: is there a role for resistance training programmes? British Journal of Sports Medicine, 43, 25–27.
Marshall, S., & Biddle, S. (2001). The transtheoretical model of behavior change: a meta-analysis of applications to physical activity and exercise. Annals of Behavioral Medicine, 23, 229–246.
Merom, D., Phongsavan, P., Wagner, R., Chey, T., Marnane, C., Steel, Z., et al. (2008). Promoting walking as an adjunct intervention to group cognitive behavioral therapy for anxiety disorders: A pilot group randomized trial. Journal Anxiety Disorders, 22, 959–968.
Miller, W., & Rollnick, S. (2002). Motivational interviewing: Preparing people for change. New York: Guilford Press.
Ng, F., Dodd, S., & Berk, M. (2007). The effects of physical activity in the acute treatment of bipolar disorder: A pilot study. Journal of Affective Disorders, 101, 259–262.
Otto, M., Church, T., Craft, L., Greer, T., Smits, J., & Trivedi, M. (2007). Exercise for mood and anxiety disorders.
Journal Clinical Psychiatry, 9, 287–294.
Prochaska, J., & Velicer, W. (1997). The transtheoretical model of health behavior changes. American Journal of Health Promotion, 12, 38–45.
Rethorst, C., Wipfli, B., & Landers, D. (2009). The antidepressive effects of exercise: A meta-analysis of random- ized trials. Sports Medicine, 39, 491– 511.
Rugulies, R. (2002). Depression as a predictor for coronary heart disease. A review and meta-analysis. American Journal of Preventive Medicine, 23, 51–61.
Salmon, P. (2001). Effects of physical exercise on anxiety, depression, and sensitivity to to stress: A unifying the- ory. Clinical Psychology Review, 21, 33–61.
Somers, J., Goldner, E., Waraich, P., & Hsu, L. (2006). Prevalence and incidence studies of anxiety disorders: A systematic review of the literature. Canadian Journal of Psychiatry, 51, 100–103.
Sonstroem, R., & Morgan, W. (1989). Exercise and self-esteem: Rationale and model. Medicine in Science & Sports Exercise, 21, 329–337.
Ströhle, A., Graetz, B., Scheel, M., Wittmann, A., Feller, C., Heinz, A., et al. (2009). The acute antipanic and anxiolytic activity of aerobic exercise in patients with panic disorder and healthy control subjects. Journal of Psychiatric Research, 43, 1013–1017.
Vancampfort, D., Sweers, K., De Hert, M., Probst, M., Knapen, J., van Winkel, R.,
et al. (in press). De test - hertest betrouwbaarheid van de 6-minuten wandeltest bij personen met schizo- frenie (The test - retest reliability of the six-minute walk test in persons with schizophrenia). Actuele themata uit de psychomotorische therapie. Leuven: Acco.
Wipfli, B., Rethorst, C., & Landers, D. (2008). Anxiolytic effects of exercise: A meta-analysis of randomized trials and dose–response analysis. Journal of Sport & Exercise Psychology, 30, 392–410.
World Health Organization. (2004). Prevention of mental disorders: Effective interventions and policy option: Summary report. Geneva: World Health Organization.
Zoeller, R. (2007). Physical activity: depression, anxiety, physical activity, and cardiovascular disease: What's the connection? American Journal of Lifestyle Medicine, 1, 175–180.
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