Radiological Characterization Of Primary Malignant Bone Tumors In Patient

Authors

  • Dr.Asaad Mousa Joudah Al-Baaj Iraqi Ministry of Health, Diwaniyah Health Dirctorate, Diwaniyah, Iraq. M.B.Ch.B. \ C.A.B.M.S. \ (Radiology) Author
  • Dr. Qassim Najem Abud Al Jenapi Iraqi Ministry of Health, Diwaniyah Health Dirctorate, Diwaniyah, Iraq. M.B.Ch.B. \ C.A.B.M.S. \ (Radiology) Author
  • Dr. Thamer Yasir Hussein Alrikabi Iraqi Ministry of Health, Thi-Qar Health Office, Thi-Qar, Iraq. M.B.Ch.B. \ C.A.B.M.S. \ (Radiology) Author

DOI:

https://doi.org/10.61841/rnwce804

Keywords:

Benign and malignant tumor, primary bone tumors

Abstract

 Bone tumors are a commonly encountered diagnostic dilemma for radiologists. Benign and malignant neoplasms, metabolic abnormalities, and tumor like conditions (reactive focal abnormalities often related to developmental or inflammatory causes) all fall under the purview of bone tumors. Primary bone tumors are rare; tumor like conditions, metastasis, and lymphohematological malignancies outnumber primary bone tumors by far. Conventional radiography is recommended as the initial imaging modality for suspected bone tumors. Radiography provides excellent resolution and yields the most useful information about the morphologic characteristics of a lesion providing important diagnostic information regarding aggressive or nonaggressive characteristics of the lesion. The combination of radiographic imaging findings, clinical information such as the age of the patient, and in some cases histology, are all essential. Rather than discussing an in-depth analysis of every bone tumor, we will instead focus on a systematic approach to the radiographic analysis of bone tumors. The figures and tables in this article will help readers become familiar with specific radiographic appearances, location, and age predilection of common bone tumors and help to organize a differential diagnosis when analyzing a bone lesion 

Downloads

Download data is not yet available.

References

1. Kumar N, Gupta B: Global incidence of primary malignant bone tumors. Curr Orthop Pract. 2016, 27:530-

4. 10.1097/BCO.0000000000000405

2. Ahmad M, Ghani A, Mansoor A, Khan AH: Pattern of malignant bone tumour in northern areas of Pakistan. JPMA.

1994, 44:203-5.

3. Rao A, Sharma C, Parampalli R: Role of diffusion-weighted MRI in differentiating benign from malignant bone

tumors. BJR Open. 2019, 1:20180048. 10.1259/bjro.20180048

4. Gemescu IN, Thierfelder KM, Rehnitz C, Weber MA: Imaging features of bone tumors: conventional radiographs

and MR imaging correlation. Magn Reson Imaging Clin N Am. 2019, 27:753-67. 10.1016/j.mric.2019.07.008

5. Pozzi G, Albano D, Messina C, et al.: Solid bone tumors of the spine: diagnostic performance of apparent diffusion

coefficient measured using diffusion-weighted MRI using histology as a reference standard. J Magn Reson Imaging.

2018, 47:1034-42. 10.1002/jmri.25826

6. Fritz B, Müller DA, Sutter R, Wurnig MC, Wagner MW, Pfirrmann CWA, Fischer MA: Magnetic resonance imagingbased grading of cartilaginous bone tumors: added value of quantitative texture analysis. Invest Radiol. 2018, 53:663-

72. 10.1097/RLI.0000000000000486

7. De Salvo S, Pavone V, Coco S, Dell’Agli E, Blatti C, Testa G: Benign bone tumors: an overview of what we know

today. J Clin Med. 2022, 11:699. 10.3390/jcm11030699

8. Farooq A, Zameer S, Khadim R, Manzoor A: Diagnostic accuracy of magnetic resonance imaging in diagnosing bone

tumors keeping histopathological correlation as gold standard. PAFMJ. 2021, 71:S207-12. 10.51253/pafmj.

v71iSuppl-1.2961.

9. Nielsen GP, Rosenberg AE, Deshpande V, Hornicek FJ, Kattapuram SV, Rosenthal DI. Diagnostic pathology: bone,

2nd ed. Philadelphia: Elsevier; 2017.

10. Unni KK, Inwards CY. Dahlin’s bone tumors, 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2010.

11. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin 2019;69:7-34.

12. ASCO. Bone Cancer: Statistics, 2020. www.cancer.net/cancer-types/bone-cancer/statistics.

13. Keel SB, Jaffe KA, Petur Nielsen G, Rosenberg AE. Orthopaedic implant-related sarcoma: a study of twelve cases.

Mod Pathol 2001;14:969-77.

14. Visuri T, Pulkkinen P, Paavolainen P. Malignant tumors at the site of total hip prosthesis. Analytic review of 46 cases.

J Arthroplasty 2006;21:311-23.

15. WHO Classification of Tumours Editorial Board. WHO classification of tumours of soft tissue and bone, 5th ed.

Lyon: IARC; 2020.

16. Eftekhari F. Imaging assessment of osteosarcoma in childhood and adolescence: Diagnosis, staging and evaluating

response to chemotherapy. Cancer Treat Res. 2009;152:33–62. doi: 10.1007/978-1-4419-0284-9_3.

17. Kaste SC. Imaging pediatric bone sarcomas. Radiol Clin North Am. 2011;49:749–765. doi: 10.1016/j.rcl.2011.05.006.

18. Costelloe CM, Madewell JE. Radiography in the initial diagnosis of primary bone tumors. AJR Am J Roentgenol.

2013;200:3–7. doi: 10.2214/AJR.12.8488.

19. Rana KA, Meyer J, Ibrahim S, Ralls M, Kent PM. The role of imaging of malignant bone tumors in children and

young adults. Curr Probl Cancer. 2013;37:181–191. doi: 10.1016/j.currproblcancer.2013.07.005.

20. Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F. World Health Organization classification of tumours of soft

tissue and bone [M] Lyon: IARC Press; 2013. pp. 264–81.

21. Lee RK, Chu WC, Leung JH, Cheng FW, Li CK. Pathological fracture as the presenting feature in pediatric

osteosarcoma. Pediatr Blood Cancer. 2013;60:1118–1121. doi: 10.1002/pbc.24447.

22. Murphey MD, Senchak LT, Mambalam PK, Logie CI, Klassen-Fischer MK, Kransdorf MJ. From the radiologic

pathology archives: Ewing sarcoma family of tumors: Radiologic-pathologic correlation. Radiographics.

2013;33:803–831. doi: 10.1148/rg.333135005.

23. Fayad LM, Jacobs MA, Wang X, Carrino JA, Bluemke DA. Musculoskeletal tumors: How to use anatomic, functional

and metabolic MR techniques. Radiology. 2012;265:340–356. doi: 10.1148/radiol.12111740.

24. Benassi MS, Rimondi E, Balladelli A, Ghinelli C, Magagnoli G, Vanel D. The role of imaging for translational

research in bone tumors. Eur J Radiol. 2013;82:2115–2123. doi: 10.1016/j.ejrad.2011.11.031.

25. Hwang S, Panicek DM. The evolution of musculoskeletal tumor imaging. Radiol Clin North Am. 2009;47:435–453.

doi: 10.1016/j.rcl.2008.12.002.

26. Meyers PA, Gorlick R, Heller G, Casper E, Lane J, Huvos AG, Healey JH. Intensification of preoperative

chemotherapy for osteogenic sarcoma: Results of the Memorial Sloan-Kettering (T12) protocol. J Clin Oncol.

1998;16:2452–2458. doi: 10.1200/JCO.1998.16.7.2452.

27. Zhang J, Cheng K, Ding Y, Liang W, Ding Y, Vanel D, Cheng X. Study of single voxel 1H MR spectroscopy of bone

tumors: Differentiation of benign from malignant tumors. Eur J Radiol. 2013;82:2124–2128.

Downloads

Published

28.02.2023

How to Cite

Mousa Joudah Al-Baaj, A., Najem Abud Al Jenapi, Q., & Yasir Hussein Alrikabi, T. (2023). Radiological Characterization Of Primary Malignant Bone Tumors In Patient. International Journal of Psychosocial Rehabilitation, 27(1), 43-50. https://doi.org/10.61841/rnwce804