Effect of isolated fatty acids from flaxseeds Linumusitatissimum against LeishmaniatropicaIn vitro.
DOI:
https://doi.org/10.61841/8axges43Keywords:
Fatty acid, flax, Linumusitatissimum, Leishmaniatropica.fatty acidsAbstract
The current study aimed to test the effectiveness of Fatty acid separation
from the seeds of the flax plant Linum usitatissimum on the parasite
Leishmaniatropica. Palmatic acid, Steric acid, Olic acid, and Arachidic acid
Behenic acid). These fatty acids were used as a possible anti-inflammatory
agents in vitro, as the results showed that the concentration of 100 μg/ml
gave a complete inhibition of the parasite’s growth in the promastigote form
in 48 hours and up by 100% compared to the control group, which
growth of the parasite was witnessed at all times, while the concentration of
25 μg/ml showed a decrease in the percentage of inhibition compared to the
rest of the concentrations, which was 78.8% at the time of 96 hours, and the
inhibitory concentration for 90% of the parasites (LC90) was at the
concentration of 50 μg/ml. milliliters at log phase 96 hours of culture. This
led to a reduction in the number of generations and an increase in the time
required to produce them compared to the control group.
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