CHARACTERIZATION OF FLAVONOID COMPOUNDS

Authors

  • Dadan Ridwanuloh Program Studi Farmasi Universitas Buana Perjuangan Karawang Author
  • Fadilah Syarif Program Studi Farmasi Universitas Buana Perjuangan Karawang Author
  • Andhi Sukma Widyatama University Author

DOI:

https://doi.org/10.61841/x7p2yf25

Keywords:

Flavonoids, P.angulata L. Phytochemistry

Abstract

The use of plants in Indonesia is widely used as herbal medicines in an effort to maintain public health. One type of plants used as herbal medicines is the Ciplukan plant, Physalis angulata L. The activity of the P.angulata L. plant is as antihyperglycemic, antibacterial, antiviral, immunostimulant and immunosuppressant (immunomodulatory), anti-inflammatory, antioxidant, and cytotoxic properties. One of the secondary metabolite compounds which has this activity is the Flavonoid group. Therefore, the purpose of this study was to identify the flavonoid compounds contained in the Ciplukan plant, P.angulata L. The methods used were Phytochomia Test, Thin Layer Chromatography, Column Chromatography, and UV-Vis Spectrophotometry. Phytochemical test results show that the Ciplukan stem contains quinone, flavonoid, saponin, and monosesquiterpeoid compounds, and polyphenols. TLC test with n-hexane-ethyl acetate (7: 3) eluent showed a blue chromatogram with Rf 0.8 cm. Several fractions of the results of the chromatography column later in UV-Vis Spectrophotometry showed the compound was a flavonoid type of flavanone. 

Downloads

Download data is not yet available.

References

[1] Achamad, S.A. 1986. Kimia Organik Bahan Alam, Materi 4: Ilmu Kimia Flavonoid. Karunia Universitas Terbuka. Jakarta. Hlm 39.

[2] Djamal, Rusdi. (2008). Prinsip-prinsip Dasar Isolasi Dan Identifikasi. Padang: Universitas Baiturrahmah.

[3] Harborne, J.B. 1987. Metode Fitokimia Penuntun Cara Modern Menganalisis Tumbuhan. Penerbit ITB. Bandung.

[4] Kusumaningtyas et al. 2015. Potential Of Ciplukan (Physalis angulate L.) As Source Of Functional Ingredient. Procedia Chemistry 14, hlm 367-372.

[5] Markham, K.R., 1988, Cara Mengidentifikasi Flavonoid. Diterjemahkan Oleh Kosasih Pandawinata, 15, Penerbit ITB, Bandung.

[6] Jabarullah, N.H. (2019) Production of olefins from syngas over Al2O3 supported Ni and Cu nano-catalysts, Petroleum Science and Technology, 37 (4), 382 – 385.

[7] Marliana, D.S., Venty, S., dan Suyono. (2005). Skrining Fitokimia Dan Analisis Kromatografi Lapis Tipis Komponen Bahan Alam Buah Labu Siam (Sechium edule Jacq. Swartz.) Dalam Ekstrak Etanol. Jurnal Biofarmasi.3(1): 29.

[8] Nurhayati T, Aryanti D, Nurjanah. 2009. Kajian Awal Potensi Ekstrak Spons Sebagai Antioksidan. Jurnal Kelautan Nasional 2:43-51.

[9] Ramesh, B. N., Mahalakshmi, A. M. 2014. Physalis angulata L.: An Ethanopharmacological Review. Indo American Journal of Pharm Research 4 (03), hlm. 1479-1486.

[10] Soetarno, S. dan Soediro, L.S., 1997, Standarisasi Mutu Simplisia Dan Ekstrak Bahan Obat Tradisional, Presidium Temu Ilmiah Nasional Bidang Farmasi.

[11] Supachok, P. & Vajrodaya, S., Comparative Phytochemistry Of Physalis angulata L. (Family Solanaceae). Short Comunication. Departemetn of Botani, Faculty of Science, Kasetsart University Bangkok.

Downloads

Published

29.02.2020

How to Cite

Ridwanuloh, D., Syarif, F., & Sukma, A. (2020). CHARACTERIZATION OF FLAVONOID COMPOUNDS. International Journal of Psychosocial Rehabilitation, 24(1), 8313-8317. https://doi.org/10.61841/x7p2yf25