Correlation between serum caspase-3 with clinical and laboratory manifestation of SLE

Authors

  • Tuqa Z. Omran Medical microbiology and immunology, Department of Medical sciences, Al-Ameed University, Kerbala, Iraq Author
  • Amna E. Al-araji Medical microbiology and immunology, Department of Medical sciences, Al-Ameed University Author
  • Shawqi W. Mohammed Ali Al Hakeem General Hospital, Al-Najaf, Iraq. Author
  • Sawsan M. Jabbar Medical Microbiology, College of Medicine, University of Kerbala. Author
  • Sabah N. Al-Fatlawi Consultant Clinical Immunology. Author

DOI:

https://doi.org/10.61841/48xeee24

Keywords:

caspase-3, SLE, apoptosis

Abstract

Background: SLE is a multisystem disease that is due to dysregulation of immune system and apoptosis process. Caspase-3 is one of the important enzymes in the apoptotic pathways. In this study we try to assess correlation between serum levels of this enzyme with some clinical and laboratory manifestations of SLE. Methods: we have enrolled 50 patients with SLE and measured their serum caspase-3 levels end have recorded some of the clinical and laboratory manifestation. Then we correlate these with corresponding serum caspase-3 levels. Results and conclusions: only Serum creatinine showed significant correlation with serum caspase-3 level 

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Published

29.02.2020

Issue

Vol. 24 No. 1 (2020): 24 (1) 2020

Section

Articles

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How to Cite

Z. Omran, T., E. Al-araji, A., W. Mohammed Ali, S., M. Jabbar, S., & N. Al-Fatlawi, S. (2020). Correlation between serum caspase-3 with clinical and laboratory manifestation of SLE. International Journal of Psychosocial Rehabilitation, 24(1), 7208-7212. https://doi.org/10.61841/48xeee24