MYCOLOGICAL STUDY OF RECURRENT APHTHOUS STOMATITIS IN SAMARRAH CITY
DOI:
https://doi.org/10.61841/f35gmj09Keywords:
RAS, Cryptococcus, laurentii, ENT, , fungal infection,, ulcerationAbstract
RAS is some of the best communal mucosal conditions of the oral cavity. The etiopathogenesis of RAS is uncertain, but influencing factors include stress, trauma, food allergy, and genetic factors. Stress and microorganisms have a role in the onset and recurrence of RAS.This study aim at clarifying the association between fungus and aphthous ulcer and detection of virulence factors .The current work represented an observational cross- sectional study which was conducted during the period extending from the first of July 2019 to the end of November 2019, with 4-5 regular working hours. The total number of patients in this study was 150 patients attending to the ENT out-patients in Sammarra General Hospital.The total number of patients with recurrent aphthous stomatitis in our study was 150 patients attending to the ENT out – patients in Sammarra General Hospital during the period between 1st of July to end of November 2019. All of these patients have recurrent aphthous stomatitis, 68 (45.33%) were male patients and 82(54.66%) were female patients, while, higher prevalence in age 21-40years 59(39.3%).In our study, the results were that fungal infection as a cause of aphthous stomatitis is infrequent, but in some cases there may be super-added fungal infection in addition to presence aphthous ulceration .
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1. Jurge S, Kuffer R, Scully C, Porter SR. Number VI recurrent aphthous stomatitis. Oral diseases. 2006 Jan;12(1):1-21.
2. Cawson RA, Odell EW. Cawson's Essentials of Oral Pathology and Oral Medicine. 8th ed. Philadelphia: Elseivier; 2008
3. Scully C, Porter S. Recurrent aphthous stomatitis: Current concepts of etiology, pathogenesis and management. J Oral Pathol Med. 1989;18:21–7
4. Preeti L, Magesh KT, Rajkumar K, Karthik R. Recurrent aphthous stomatitis. Journal of oral and maxillofacial pathology: JOMFP. 2011 Sep;15(3):252.
5. Stanley HR: Aphthous lesions. Oral Surg 33:407-416, 1972.
6. Field EA, Allan RB. Oral ulceration–aetiopathogenesis, clinical diagnosis and management in the gastrointestinal clinic. Alimentary pharmacology & therapeutics. 2003 Nov;18(10):949-62.
7. Almoznino G, Zini A, Mizrahi Y, Aframian DJ. Elevated serum I g E in recurrent aphthous stomatitis and associations with disease characteristics. Oral diseases. 2014 May;20(4):386-94.
8. Bazrafshani MR, Hajeer AH, Ollier WE, Thornhill MH. IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS). Genes and immunity. 2002 Aug;3(5):302.
9. Albanidou‐Farmaki E, Deligiannidis A, Markopoulos AK, Katsares V, Farmakis K, Parapanissiou E. HLA haplotypes in recurrent aphthous stomatitis: a mode of inheritance?. International journal of immunogenetics. 2008 Dec;35(6):427-32.
10. Hoover CI, Olson JA, Greenspan JS. Humoral responses and cross-reactivity to viridans streptococci in recurrent aphthous ulceration. Journal of dental research. 1986 Aug;65(8):1101-4.
11. Natah SS, Konttinen YT, Enattah NS, Ashammakhi N, Sharkey KA, Häyrinen-Immonen R. Recurrent aphthous ulcers today: a review of the growing knowledge. International journal of oral and maxillofacial surgery. 2004 Apr 1;33(3):221-34.
12. Hunter IP, Ferguson MM, Scully C, Galloway AR, Main AN, Russell RI. Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy. Oral surgery, oral medicine, oral pathology. 1993 May 1;75(5):595-8.
13. Tarakji B, Baroudi K, Kharma Y. The effect of dietary habits on the development of the recurrent aphthous stomatitis. Nigerian medical journal: journal of the Nigeria Medical Association. 2012 Jan;53(1):9.
14. Koybasi S, Parlak AH, Serin E, Yilmaz F, Serin D. Recurrent aphthous stomatitis: investigation of possible etiologic factors. American journal of otolaryngology. 2006 Jul 1;27(4):229-32.
15. Hunter IP, Ferguson MM, Scully C, Galloway AR, Main AN, Russell RI. Effects of dietary gluten elimination in patients with recurrent minor aphthous stomatitis and no detectable gluten enteropathy. Oral surgery, oral medicine, oral pathology. 1993 May 1;75(5):595-8.
16. Tarcin BG. Oral candidosis: aetiology, clinical manifestations, diagnosis and management. Clinical and Experimental Health Sciences. 2011 May 1;1(2):140.
17. Floto RA, Smith KG. The vagus nerve, macrophages, and nicotine. The Lancet. 2003 Mar 29;361(9363):1069-70.
18. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Philadelphia: Saunders Elsevier. p. 308.
19. Kerawala C, Newlands C (editors) (2010). Oral and maxillofacial surgery. Oxford: Oxford University Press. pp. 446, 447.
20. Anil Ghom; Shubhangi Mhaske (2010). Textbook of oral pathology. New Delhi: Jaypee Brothers Medical Publishers. pp. 498, 508–514.
21. Singh, Rachna; Chakrabarti, Arunaloke ( 2017 ) . "Invasive Candidiasis in the Southeast-Asian Region". In Prasad, Rajendra ( ed. ) . Candida albicans : Cellular and Molecular Biology ( 2 ed. ) . Switzerland : Springer International Publishing AG. p. 27. ISBN 978-3-319- 50408-7
22. Odds FC, Bernaerts RI. CHROMagar Candida, a new differential isolation medium for presumptive identification of clinically important Candida species. Journal of clinical microbiology. 1994 Aug 1;32(8):1923-9.
23. Arnaud MB, Binkley J, Shah P, Skrzypek MS, Wymore F, Binkley G, Miyasato SR, Simison M, Sherlock
G. The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrata. Nucleic acids research. 2011 Nov 7;40(D1):D667-74.
24. Barnett JA, Payne RW, Yarrow D. Yeasts: characteristics and identification. Cambridge University Press (CUP) Cambridge; 1990.
25. Gupta A. Fatal Candida famata peritonitis complicating sclerosing peritonitis in a peritoneal dialysis patient. Nephrol. Dial. Transplant.. 2006;21:2036-7.
26. Diekema DJ, Messer SA, Brueggemann AB, Coffman SL, Doern GV, Herwaldt LA, Pfaller MA. Epidemiology of candidemia: 3-year results from the emerging infections and the epidemiology of Iowa organisms study. Journal of Clinical Microbiology. 2002 Apr 1;40(4):1298-302.
27. Gordon L. Love, MD, chair of the Department of Pathology, Louisiana State University School of Medicine, and director of laboratories, University Medical Center, New Orleans; and Julie A. Ribes, MD, PhD, a professor of pathology and laboratory medicine and the director of the clinical microbiology laboratory and assistant director of special chemistry, infectious disease serology, University of Kentucky Medical Center, Lexington).
28. JOURNAL OFCLINICALMICROBIOLOGY,0095-1137/01/$04.0010 DOI: 10.1128/JCM.39.4.1608–
1611.2001Apr. 2001, p. 1608–1611).
29. Chand-Goyal T, Spotts RA. Enumeration of bacterial and yeast colonists of apple fruits and identification of epiphytic yeasts on pear fruits in the Pacific Northwest United States. Microbiological research. 1996 Dec 1;151(4):427-32.
30. Custis PH, Haller JA. An unusual case of cryptococcal endophthalmitis. Retina (Philadelphia, Pa.). 1995;15(4):300-4.
31. Lynch III JP, Schaberg DR, Kissner DG, Kauffman CA. Cryptococcus laurentii lung abscess. American Review of Respiratory Disease. 1981 Jan;123(1):135-8.
32. Atlas RA. Handbook of Microbiological Media. CRC Press, Ann Arbor. 1993.
33. Barnett JA, Payne RW, Yarrow D, editors. Yeasts: Characteristics and Identification, 3rd ed. Cambridge University Press, New York. 2000.
34. Byahatti SM. Incidence of Recurrent Apthous ulcers in a group of student population in Libya: A Questionnaire Study. Arch Cran Oro Fac Sc. 2013;1(2):26-30.
35. Abdullah MJ. Prevalence of recurrent aphthous ulceration experience in patients attending Piramird dental speciality in Sulaimani City. Journal of clinical and experimental dentistry. 2013 Apr;5(2):e89.
36. Donatsky O. Epidemiologic study on recurrent aphthous ulcerations among 512 Danish dental students. Community dentistry and oral epidemiology. 1973 Oct;1(1):37-40.
37. Axéll T. A prevalence study of oral mucosal lesions in an adult Swedish population. Odontologisk Revy. Supplement. 1976;36:1-03.
38. Evans GW, English K. The environment of poverty: Multiple stressor exposure, psychophysiological stress, and socioemotional adjustment. Child development. 2002 Jul;73(4):1238-48.
39. Bierhaus A, Wolf J, Andrassy M, Rohleder N, Humpert PM, Petrov D, Ferstl R, von Eynatten M, Wendt T, Rudofsky G, Joswig M. A mechanism converting psychosocial stress into mononuclear cell activation. Proceedings of the National Academy of Sciences. 2003 Feb 18;100(4):1920-5.
40. Dooley MA, Hogan SL. Environmental epidemiology and risk factors for autoimmune disease. Current opinion in rheumatology. 2003 Mar 1;15(2):99-103.
41. Bittoun R. Recurrent aphthous ulcers and nicotine. Medical journal of Australia. 1991 Apr;154(7):471-2.
42. Tüzün B, Wolf R, Tüzün Y, Serdaroğlu S. Recurrent aphthous stomatitis and smoking. International journal of dermatology. 2000 May;39(5):358-60.
43. Atkin PA, Xu X, Thornhill MH. Minor recurrent aphthous stomatitis and smoking: an epidemiological study measuring plasma cotinine. Oral diseases. 2002 May;8(3):173-6.
44. Shapiro S, Olson DL, Chellemi SJ. The association between smoking and aphthous ulcers. Oral Surgery, Oral Medicine, Oral Pathology. 1970 Nov 1;30(5):624-30.
45. Filiz Ee, Öztürkcan S, Yüceyar H, Kandiloğlu Ar, Şendil Az. Rekürren aftöz stomatit etiyolojisinde Helikobakter pilorinin rolü. Turkiye Klinikleri Journal of Dermatology. 2002;12(2):61-5.
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