The Effect of NPK and Microbial Consortium on Organosulfur Content: Natural Anti-Diabetes and Efforts to Reduce the Psychological Pressure Level of Diabetics
DOI:
https://doi.org/10.61841/gma50t68Keywords:
Diabetes, Garlic, Organosulfur,, Psychological Pressure.Abstract
Had been conducted a research about the effect of NPK and the microbial consortium on organosulfur compounds and their effect as antidiabetic. The study was carried out at Vegetable Research Institute (Balitsa) Lembang from October to December 2019. This study used a completely randomized design with 6 treatments and 3 replications on garlic cv. Lumbu Kuning. The observation parameter was organosulfur compounds which were then applied to 6 lab mice with 100% organosulfur concentration. A questionnaire was also distributed to 100 diabetic patients in Bandung City to determine the psychological conditions of the patients before and after knowing the benefits of organosulfur. The analysis showed that the microbial consortium had a good influence on organosulfur enhancement. Organosulfur was able to reduce glucose levels in mice by 78.64%. Diabetic patients experienced a 15% decrease in anxiety after gaining an understanding of the organosulfur effects.
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References
[1] Khairani, “Hari Diabetes Sedunia Tahun 2018,” Pus. Data dan Inf. Kementrian Kesehat. RI, pp. 1–8, 2019.
[2] R. Lisiswanti and F. P. Haryanto, “Allicin Pada Bawang Putih (Allium sativum) Sebagai Terapi Alternatif Diabetes Melitus Tipe 2,” J. Major., vol. 6, no. 2, pp. 33–38, 2017.
[3] J. Wang, X. Zhang, H. Lan, and W. Wang, “Effect of garlic supplement in the management of type 2 diabetes mellitus (T2DM): A meta-analysis of randomized controlled trials,” Food Nutr. Res., vol. 61, no. 1, 2017, doi: 10.1080/16546628.2017.1377571.
[4] U. Hernawan, “Senyawa Organosulfur Bawang Putih ( Allium sativum L .) dan Aktivitas Biologinya Aktivitas Biologinya,” Biofarmasi Jur. Biol. FMIPA UNS, vol. 1, no. August 2003, pp. 64–76, 2014.
[5] J. D. Donsu, M. N. R. Hadjam, A. H. Asdie, and R. Hidayat, “Peran Faktor-faktor Psikologis terhadap Depresi pada Pasien Diabetes Mellitus Tipe 2,” J. Psikol., vol. 41, no. 2, p. 241, 2014, doi: 10.22146/jpsi.6953.
[6] B. P. Cahya, C. Mambo, and M. P. Wowor, “Uji Efek Ekstrak Umbi Bawang Putih (Allium Sativum l.) Terhadap Kadar Glukosa Darah Tikus Wistar (Rattus Norvegicus) Yang Diinduksi Aloksan,” Jurnal e- Biomedik (eBm). vol. 3, no. 1, 2015.
[7] K. Charu, S. Yogita, and S. Sonali, “Neutraceutical potential of organosulfur compounds in fresh garlic and garlic preparations,” Int. J. Pharma Bio Sci., vol. 5, no. 1, 2014.
[8] G. Widakdo and Besral, “Efek Penyakit Kronis terhadap Gangguan Mental Emosional [Effects of Chronic Disease on Emotional Mental Disorders],” J. Kesehat. Masy. Nas., vol. 7, no. 7, pp. 309–316, 2013, doi: http://dx.doi.org/10.21109/kesmas.v7i7.29.
[9] Hernawan, U. “Senyawa Organosulfur Bawang Putih ( Allium sativum L .) dan Aktivitas Biologinya Aktivitas Biologinya”. Biofarmasi Jurusan Biologi FMIPA UNS, 1(August 2003), pp. 64–76, 2014.
[10] Jain SK, Rains J, Jones K. “Effect of curcumin on protein glycosylation, Lipid peroxidation, and oxygen radical generation in human red blood cells exposed to high glucose levels.” Free Radic Biol Med, 41:92–6, 2006.
[11] Davies T, Craig TK. ABC kesehatan mental. Alifa Dimanti, penerjemah. Jakarta: Buku Kedokteran EGC; 2009.
[12]. Widakdo, G. and Besral. “Efek Penyakit Kronis terhadap Gangguan Mental Emosional [Effects of Chronic Disease on Emotional Mental Disorders]”, Jurnal Kesehatan Masyarakat Nasional, 7(7), pp. 309–316. 2013, doi: http://dx.doi.org/10.21109/kesmas.v7i7.29.
[13] Butt MS, Sultan MT. “Garlic: nature’s protection against physiological threats. Critical Reviews in Food Science and Nutrition, 49(6):538-51, 2009
[14] Sargyn, H., & Sargyn, M. “Diabetes and Depression.” Journal of Endocrinology and Metabolism, 3, 95-100, 2002.
[15] Kinder, L.S., Katon, W.J. Ludman, E., Russo, J., Simon, G., Lin, E.H.B. “Improving depression care in patients with diabetes and multiple complications.” Journal General Medic, 21, 1036- 1041, 2006.
[16] M. S. Panasiti, C. Violani, and C. Grano, “Exploring the relationship between umbilical blood cord and trust,”
Int. J. Psychol. Int., pp. 1–8, 2020, doi: 10.1002/ijop.12664.
[17] Manafikhi R, Kalie L, Lahdo R. "Effects of garlic supple- mentation on fasting blood sugar, HbA1c and lipid profile in type 2 diabetics receiving metformin and glyburide." Int J Acad Scientific Re, vol. 3 no. 5 pp11–18, 2015.
[18] Atkin M, Laight D, Cummings MH. "The effects of garlic extract upon endothelial function, vascular inflamma- tion, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial." J Diabetes Complications. no30, pp723–727, 2016.
[19] Ames, M. E., Rawana, J. S., & Gentile, P. “The protective role of optimism and self-esteem on depressive symp- tom pathways among Canadian Aboriginal youth. Journal of Youth and Adolescence. Advance Online Publi-cation. 2013. doi: 10.1007/s10964-013-0016-4.
[20] Berge LI, Riise T. Comorbidity between Type 2 Diabetes and Depression in the Adult Population: Directions of the Association and Its Possible Pathophysiological Mechanisms. Int J Endocrinol. 2015; 2015:164760. 16.
[21] Moulton CD, Pickup JC, Ismail K. The link between depression and diabetes: the search for shared mechanisms. Lancet Diabetes Endocrinol. 2015; 3:461-471
[22] Islam, Z., Rusdi, N. K., & Nurhasanah. “Analisis Perbedaan Pengobatan Diabetes Melitus Tipe II Pada Pasien BPJS Dan Pasien Umum”. Media Farmasi, 14(2), 151–161, 2014.
[23] Agardh E, Allebeck P, Hallqvist J, Moradi T, Sidorchuk A. Type 2 diabetes incidence and socio-economic position: a systematic review and meta-analysis. Int J Epidemiol. 2011; 40:804-818.
[24] Tattelman, E. “Health effect of garlic”. Am Fam Physician,72(1);103-6., 2005.
[25] Kalay, A. M., Uluputty, M. R., Leklioy, J. M. A., & Hindersah, R. “Aplikasi Pupuk Hayati Konsorsium Dan Inokulan Padat Trichoderma harzianum Terhadap Produktivitas Tanaman Sawi Pada Lahan Terkontaminasi Rhizoctonia solani Application Of Trichoderma harzianum Solid Inokulan And Biofertilizer Consortium On Choy Sum Product.” Agrologia, 5(2), 78–86, 2016.
[26] Nemiary D, Shim R, Mattox G, Holden K. “The relationship between obesity and depression among adolescents.” Psychiatr Ann; 42(8):305-8, 2012.
[27] Fares, A.Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients(2011) Journal of Cardiovascular Disease Research, 2 (3), pp. 153-155.
DOI: 10.4103/0975-3583.85261
[28] Raheem farista, pradeep m muragundi (2016) practical possibilities to empower patients in management of inflammatory bowel disease. Journal of Critical Reviews, 3 (4), 1-5.
[29] Parimalakanthi, K., Kumar, M.A.A Study on Investment Preference and behaviour of Individual Investors in
Coimbatore City K(2015) Bonfring International Journal of Industrial Engineering and Management Science, 5 (4), pp. 170-174.
[30] Mensky, M.B. Mathematical models of subjective preferences in Quantum concept of consciousness (2011)
NeuroQuantology, 9 (4), pp. 614-620
[31] Anand Nayyar, Dac Binh Ha, Ranbir Singh Batth, G. Sussendran, ”Opportunistic Networks: Present Scenario- A Mirror Review” International Journal of Communication Networks and Information Security (IJCNIS), Vol. 10, No. 1, pp.223-241April 2018 (UGC Approved Journal List No. 2747)
[32] Muneer Ahmad, Noor Zaman and Muhammad Amin., “An Experimental Research in Health Informatics for Enhancing Ovarian Cancer Identification in Ovarian Imaging Analysis Using Fuzzy Histogram Equalization”, Journal of Medical Imaging and Health Informatics, Vol 7. 2017
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