Carcinogenesis, The Role of Genetic Research in the Fight Against Cancer, Atlas of the Cancer Genome
DOI:
https://doi.org/10.61841/62hhpp61Keywords:
Sequencing, Cancer, Proto-oncogene, Anti-oncogene, CGA - Cancer Genome Atlas, DNA - Deoxyribonucleic AcidAbstract
The lecture is devoted to the role of genetic research in understanding carcinogenesis and finding the ways to treat cancer in the light of recent advances in medical genetics. The creation of a detailed catalogue of cancer genes is an important task, the accomplishment of which will allow us to select the optimal cancer therapy for each patient. To compile a catalogue of cancer genes mutating with high (>20%) and medium (2-20%) frequency, it is required to analyze 2,000 pairs of “tumor-norm” on average for each gene; that is about 100,000 pairs for the 50 most common types of cancer. Now, it no longer raises any insurmountable problem, as the cost of DNA sequencing has decreased a millionfold over the last 10 years and will continue to decrease.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 AUTHOR
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
