The Immunomodulation Effect of Staphyloxanthin Produced by Staphylococcus Aureus

Authors

  • Fatima Amer Abd Algabar Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq Author
  • Ali Hussein Alwan Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq Author
  • Khawlah Jebur Khalaf Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq Author
  • Sawsan Hassan Authman Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq Author

DOI:

https://doi.org/10.61841/3gp4ad48

Keywords:

staphyloxanthin, antimodulatar, purification, cytokines

Abstract

The results was indicated from a total of(70) isolate of staphylococcus (22.8%) isolated from 306 sample of different clinical sources that is primary diagnosis as S. aureus depending on cultural, morphological and biochemical test were collected from patients suffering from different disease infection such as wound ,UTI ,blood , eye , vagina , tonsil , nasal , burn infections and Bacteremia who had certain clinical. And the burn, wound and Nasal infection was the most accessible site for S. aureus (30.8 ,30.8,29.8)% respectively .the results was indicated the skim milk agar was the best medium of staphyloxanthin production , therefore the optimum condition of pigment production at 37°C for 72 hr .the extraction of staphyloxanthin was recorded highly significant by ethyl acetate and ethanol method . the column chromatography method used to purification of staphyloxanthin extract. as well as the results was recorded the antimodultory effect of staphyloxanthin (crude and partied in vivo and increasing in level of cytokines that induced by extracts effect). Conclusion: Staphyloxanthin acts as anti-oxidant ,anti-inflammatory ,as well as the carotenoid molecules could play an important role in regulation of the immune response. therefore staphyloxanthin represented as antimodulater effect during infection .

 

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Published

31.10.2020

Issue

Vol. 24 No. 8 (2020): 24 (8) 2020

Section

Articles

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How to Cite

Algabar, F. A. A., Alwan, A. H., Khalaf, K. J., & Authman, S. H. (2020). The Immunomodulation Effect of Staphyloxanthin Produced by Staphylococcus Aureus. International Journal of Psychosocial Rehabilitation, 24(8), 4419-4430. https://doi.org/10.61841/3gp4ad48