Assessment of “Non-Surgical Periodontal Therapy” on “Chronic Renal Disease” Patients - A Systematic Review Protocol
DOI:
https://doi.org/10.61841/ppd7mq32Keywords:
CRD, Periodontal diseases, NSPT, Cochrane methodologyAbstract
Background: Periodontal diseases are recognized as one of the risk factor responsible for various systemic diseases like insulin dependent or non-insulin dependent diabetes, cardiovascular abnormalities, pulmonary disorders, and chronic renal diseases (CRD). Arguably, subjects diagnosed with end-stage renal failure (ESRF) and the individuals receiving haemodialysis are more prone to periodontal tissue destruction and other deteriorating oral health related consequences. A higher “gingival index” and “bleeding on probing”, increased “pocket depths”, and greater “attachment loss” has been reported in patients with chronic renal failure (CRF). This could possibly be due to higher plaque indices reported in the dialysis and predialysis groups. In addition, more rapid calculus formation seen in dialysis patients than the systemically healthy individuals may be seen due to high salivary “urea” and “phosphate” levels. An improvement in the glomerular filtration rate has been observed after non-surgical periodontal therapy (NSPT) due to a decrease in the levels of inflammatory mediators that results in improving the periodontal status. Objectives: To evaluate the efficiency of NSPT in improving the periodontal health parameters, and thereby its effect on the renal parameters in patients suffering from CRD. Search Methods: We will search PUBMED without language restrictions up to NOVEMBER 2018. We will also search for ongoing studies in trial registers, perform handsearching, and check bibliographic references of relevant articles to seek potentially relevant research. We won’t apply any restrictions on language, date, or publication status. Selection Criteria: For execution of the review we are planning to include “randomized controlled trials” with parallelgroup or cross-over designs. Participants in the review will be adults aged 18 years and above with CRD and chronic periodontitis. COLLECTION OF DATA AND ITS ANALYSIS: Each individual study will independently be assessed by three review authors for its eligibility. Data extraction will then be executed by three review authors and will further be assessed for the “risk of bias” for each study independently using standard “Cochrane methodology”. We will assess the evidences using “GRADE” and will create a table for “Summary of findings”.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
